| 대한안과학회 학술대회 발표 연제 초록 |
| 망막 F-042 |
| 낭포황반부종을 동반한 망막색소변성환자의 빛간섭단층혈관조영술 분석 |
울산대학교 의과대학 서울아산병원 안과학교실 |
| 여준형, 김윤전, 윤영희 |
목적 : To investigate the microstructure of cystoid macular edema (CME) in retinitis pigmentosa (RP) patients and its association with vascular changes using optical coherence tomography (OCT) angiography (OCTA). 방법 : In this retrospective, we included 42 eyes of 21 patients with RP and age-matched healthy controls subjected to both OCT and OCTA. Using OCT, spatial distribution and the retinal layer where the CME existed were examined. En face OCTA images of the superficial and deep capillary plexus (SCP, DCP) were obtained using AngioVue (Optovue Inc.). Foveal and parafoveal flow density (FFD, PFD) in each layer and foveal avascular zone (FAZ) area were measured. 결과 : Of the 42 eyes with RP, 32 had CME and 10 eyes did not. CME was located in the inner nuclear layer in all CME eyes and limited to the parafovea. The outer nuclear layer/ganglion cell layer was also involved in 12 eyes (37.5%). The PFD values measured in SCP and DCP in RP were significantly lower than corresponding values in normal controls. However, compared to RP patients without CME (RP-nonCME), RP patients with CME (RP-CME) showed no significant differences in flow density in the SCP, DCP, or FAZ areas. No focal vascular disruption or capillary dropout, especially in CME areas, was detected 결론 : Compared with RP-nonCME, RP-CME showed no significant difference in flow density or extent of focal disruption within individual retinal layers, especially in DCP. Our findings support the hypothesis that the pathogenesis of RP-CME differs from that of retinal vascular CME triggered by compromised DCP. |