대한안과학회 학술대회 발표 연제 초록
 
망막 F-003
전망막광응고술이 시행된 눈에서 증식당뇨망막병증 유리체출혈이 발생한 경우 유리체강내 베바시주맙 주사의 유효성 평가

서울특별시 보라매병원 안과 서울대학교 의과대학 안과학교실
박영주(1,2), 안지윤(1,2), 박상준(1,3), 주광식(1,3), 신주영(1,2)

목적 : To investigate the efficacy of intravitreal bevacizumab injections (IVBs) in vitreous hemorrhage (VH) in proliferative diabetic retinopathy (PDR) with prior standard panretinal photocoagulation(PRP).
방법 : Retrospective review of patients who visited SNU-SMG Boramae Medical Center and Seoul National University Bundang Hospital between June 2006 and June 2019 with a new VH in eyes with PDR with previous standard PRP was done. Main outcome measure was the cumulative rates of spontaneous clear-up and vitrectomy. Wilcoxon statistic was used for comparison.
결과 : 44 eyes with IVB treatment and 92 control eyes without IVB were included. Mean age was younger in the IVB group than the control (53.0 vs 59.2 years, p<.001). Follow-up duration were 18.1 (IVB group) and 21.1 months (control, p=.486). Additive PRP was done in the 22 eyes (50%, IVB group) and 38 eyes (41.3%, control, p=.339). Cumulative probability for spontaneous clear-up at 12 months was 0.73 (IVB group) and 0.65 (control), higher in the IVB group (p=.026). Cumulative probability for vitrectomy at 12 months was 0.16 (IVB group) and 0.42 (control), lower in the IVB group(p=.003)
결론 : This study shows that IVB treatment can induce spontaneous clear-up of VH and defer vitrectomy in PDR patients with prior standard PRP. IVB treatment can be considered as a potential treatment option as well as additive PRP.
 
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