| 대한안과학회 학술대회 발표 연제 초록 |
| 녹 F-003 |
| 시신경 출혈이 있는 녹내장 환자에서 혈관빛간섭단층촬영검사시 혈압의 영향 |
메리놀병원 안과학교실(1) 연세대학교 의과대학 안과학교실 시기능개발 연구소(2) 국민건강보험 일산병원 안과학교실(3) |
| 박찬금(1), 이광현(2), 김은우(2), 김상아(3), 이상엽(2), 김찬윤(2), 성공제(2), 배형원(2)* |
목적 : Purpose: The association between retinal microvascular structure and glaucoma has been revealed in multiple studies using optical tomography angiography (OCTA). Recently, the vessel density (VD) of the macular area has been studied for various applications such as diagnosis, assessment, and estimation of visual function in glaucoma. In this study, we tried to identity the factors that affected macular VD (mVD) in glaucomatous eyes 방법 : Methods: OCT and OCTA images were collected in a retrospective, cross-sectional observational study from 92 eyes from 58 healthy subjects and 179 eyes from 103 glaucoma patients using the SD-OCT database of patients treated from July 2017 to July 2018. Glaucomatous eyes were further divided into two groups according to history of disc hemorrhage (DH). Association between mVD and demographic characteristics, ganglion cell-inner plexiform layer (GCIPL) thickness, visual field mean deviation (MD), and systemic blood pressure were analyzed in each subgroups. 결과 : Results: In both healthy and glaucomatous eyes, mVD was inversely associated with the age (β = -0.035, P = 0.025; β = -0.039, P = 0.018). In the glaucomatous eyes, mVD was significantly decreased as the MD value was worse (β = 0.109, P = 0.002). In the glaucomatous eyes with DH, the mVD decreased as the blood pressure increased (β = -0.111, P = 0.003) but the other factors were not significantly associated with mVD. 결론 : Conclusions: Reduced mVD is more common in older individuals in both healthy and glaucomatous eyes. mVD also correlates with the severity of MD value in glaucomatous eyes. In glaucomatous eyes with DH, high systemic BP is associated with a reduction in mVD. This may indicate that glaucoma patients with DH are more susceptible to vascular damage secondary to hypertension. |