| 대한안과학회 학술대회 발표 연제 초록 |
| 녹 F-004 |
| 정상근시안에서 비시신경유두인접 미세혈관소실의 미세구조 |
1경상의대 안과학교실, 경상대학교병원 2서울의대 안과학교실, 분당서울대학교병원 |
| 김규남1, 이은지2, 김태우2 |
목적 : To characterize the microstructure of the nonjuxtapapillary microvasculature dropout (MvD) in healthy myopic eyes. 방법 : This cross-sectional study was conducted at a tertiary referral center in Korea, and included 50 eyes (25 eyes with a nonjuxtapapillary MvD and 25 age-matched eyes without any MvD) from a cohort of 126 nonglaucomatous healthy myopic eyes having parapapillary atrophy (PPA) γ-zone. The parapapillary deep-layer microvasculature was evaluated in en-face images obtained using swept-source optical coherence tomography (OCT) angiography (OCTA). Enhanced depth-imaging OCT scanning was performed to assess the parapapillary microstructure. 결과 : The parapapillary microstructure at the nonjuxtapapillary MvD in 18 eyes was characterized by the absence of Bruch’s membrane (BM)–retinal pigment epithelium (RPE) complex, and the presence of the inner retina and sclera, suggesting that the BM-RPE complex had been dragged in a temporal direction. In seven eyes with a nonjuxtapapillary MvD but without such dragged BM-RPE complex, RPE atrophy was observed at the location of the nonjuxtapapillary MvD. Eyes with a nonjuxtapapillary MvD had a longer AXL (P = .013) and a wider γ-zone (P < .001) than age-matched control eyes without any MvD. 결론 : Nonjuxtapapillary MvD was observed in the distal portion of PPA in nonglaucomatous healthy myopic eyes. The microstructure at the nonjuxtapapillary MvD was characterized by temporally dragged BM-RPE complex, which might have been caused by stretching during axial elongation exposing the underlying sclera. Although the clinical importance of the nonjuxtapapillary MvD remains to be determined, it should be differentiated from the parapapillary choroidal MvD observed in glaucoma. |