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목적 : To investigate the structure-function relationship and the vision-related quality of life (VR-QoL) between patients with uveitic glaucoma (UG) and primary open angle glaucoma (POAG).
방법 : In this study, 69 patients with UG and 138 age- and average peripapillary retinal nerve fiber layer thickness (RNFLT)-matched POAG patients were included. The National Eye Institute Visual Function Questionnaire(NEI-VFQ-25) was used to evaluate patients’ visual function. The mean deviation (MD) of whole, superior and inferior hemifields of the affected eyes and integrated visual field (IVF) using best-location method were calculated. In each group, we analyzed the correlations of the subscales and composite scores of the NEI VFQ-25 with each calculated MD using Spearman correlation.
결과 : There was no significant difference in MDs of IVF between groups. However, the MD of the affected eyes was worse in UG group than in POAG group(p=0.012). The MD of inferior VF was more deteriorated in UG group(p=0.045), while superior RNFLT was not significantly different. UG group showed lower values in distance vision, role difficulties, peripheral vision and composite scores than POAG group(p<0.05). In POAG group, MD of affected eyes and IVF were significantly associated with 8 subscales and composite scores, whereas MD of the affected eyes was associated with 3 subscales in UG group.
결론 : At a given level of RNFLT, UG eyes showed more deteriorated VF threshold values at the inferior hemifield compared with POAG eyes. UG eyes suffered more deteriorated VR-QoL than POAG eyes and inferior VF of the affected eyes were found to be the strongest determinant of VR-QoL in UG eyes.
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