| 발표일자: |
2019년 11월 1일(금)~3(일) |
| 발표번호: |
P(e-poster)-302 |
| 발표장소: |
B3 Parking Area
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| Myelin oligodendrocyte glycoprotein (MOG) 항체 양성 시신경 환자와 특발성 시신경주위염 환자간의 연관성 연구 |
| 서울대학교 의과대학 안과학교실 (1), 서울대학교 의과대학 신경과학교실 (2) |
| 정재호 (1), 장연지 (1), 윤영인 (1), 이행진 (1), 김성준 (1), 김성민 (2) |
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목적 : To compare the clinical features, radiologic findings, and disease courses between presumed idiopathic OPN and antibody against myelin oligodendrocyte glycoprotein (MOG-Ab) associated optic neuritis (ON).
방법 : The medical records of 48 patients with MOG-Ab associated optic neuritis from 2011 to 2018 and 10 patients with presumed idiopathic OPN from 2009 to 2011 were reviewed. The clinical features, radiologic finding, and disease course of the patients with MOG-Ab associated ON and presumed idiopathic OPN were compared.
결과 : Fifteen patients had optic nerve sheath enhancement among the patients with MOG-Ab associated ON. MOG-IgG associated ON patients with optic nerve sheath enhancement had similar clinical features, radiologic findings and disease course to the patients with presumed idiopathic OPN. On the other hand, MOG-IgG associated ON patients without optic nerve sheath enhancement demonstrated different clinical features to the presumed idiopathic OPN.
결론 : Autoantibody against to MOG could be a cause of acute optic neuropathy with optic nerve sheath inflammation, therefore, MOG-Ab test should be considered in the case of presumed idiopathic OPN.
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