|
목적 : This study aimed to compare clinical characteristic of Miller Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis (BBE).
방법 : We consecutively recruited 67 patients with anti-GQ1b antibody syndrome in 2 university based hospital between 2005 and 2019. Antecedent infection, other cranial nerve involvement, strabismus pattern in primary position were analyzed.
결과 : Among 67 patients with anti-GQ1b antibody syndrome, 58 patients were MFS or MFS variant, and 9 (13.4%) patients were BBE. Antecedent infection was noted in 54 patients. Among these, 33 patients (61.1%) had upper respiratory infection, 19 patients (35.2%) had gastrointestinal infection, 2 patients (3.7%) had combined form. The time to complete recovery was 36.3 ± 68.7 weeks (range,3 to 526 weeks). It did not differ in 2 group (P=0.266). Bulbar palsy was noted in 13/58 (22.4%) patients with MFS and 88.9% in BBE (P<0.001). The internal ophthalmoplegia was noted in 3/58 MFS and 2/7 BBE (P=0.130).
결론 : We found that bulbar palsy is more common and age at onset was slightly younger in BBE. However, other clinical characteristics were similar between MFS and BBE. Therefore, When we diagnose these disease, we should note the fine point of difference.
|