| International FP-001 |
| Long term change of the optic disc during myopic shift in children with large cup to disc ratio |
| Department of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea(1)
Department of Ophthalmology, St. Vincent’s Hospital, College of Medicine, Catholic University of Korea, Suwon, Korea(2) |
| Ye Jin Ahn(1), Yoo Yeon Park(1), Yeon Woong Chung(2), Shin Hae Park(1), Sun Young Shin(1) |
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Purpose : Progressive disc tilting and the development or enlargement of peripapillary atrophy (PPA) are observed during a myopic shift in children. However, not much in known about how the optic disc changes in children with large cup to disc ratio (CDR). The aim of this study was to compare the functional and morphological changes in the optic disc induced by myopic shift during childhood between eyes with enlarged CDR (≥0.6) and normal control eyes.
Methods : A total of 82 eyes from 82 subjects under the age of 15 years were included in this study. Serial disc photographs were taken and the horizontal disc diameter (HDD), vertical disc diameter (VDD), and the maximum PPA width (PPW) were measured. Retinal nerve fiber layer(RNFL)과 ganglion cell-inner plexiform layer (GCIPL) thickness were measured using spectral domain-OCT (SD-OCT). All ocular parameters were compared at initial and at last follow-up, and the changes were analyzed.
Results : 42 eyes with large CDR (≥0.6) and 40 eyes with normal optic disc appearance were analyzed. The mean age of the large CDR group was 8.05±3.26 years and 7.34±3.03 years (p=0.33) in the control group. The mean follow-up period was 52.55±22.02 months in the large CDR group and 51.70±23.25 months in the control group (p=0.87). The degree of myopic shift and axial elongation during follow-up period were not significantly different between groups (p=0.43, p=0.31, respectively). The morphologic changes of the optic disc, represented as changes in HDD/VDD and PPW/VDD ratios did not differ between the two groups (p=0.45, p=0.62, respectively). RNFL and GCIPL thickness changes were also not significantly different (p=0.74, p=0.79, respectively).
Conclusion : During myopic shift, disc tilting and development/enlargement of PPA were also observed in children with large CDR. However, these morphologic changes were not different compared to those with normal children and no functional defects were detected.
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