| International FP- 006 |
| Multicolor imaging in central serous chorioretinopathy – a quantitative and qualitative comparison with fundus autofluorescence |
| 1) Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India.
2) Ophthalmology and Visual Sciences department, Khoo Teck Puat Hospital(KTPH), 90 Yishun Central, Singapore
3) Unit of Macula, Oftalvist Clinic, Valencia, Spain.
4) Department of Retina, Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, India.
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| Vishal Govindahari1, Sumit Randhir Singh1, Bindu Rajesh2, Roberto Gallego-Pinazo3, Rosa Dolz Marco3, Dhanya V Nair4, Unni Nair4, Jay Chhablani1
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Purpose : To conduct a qualitative and quantitative comparison of imaging findings on multicolor imaging (MCI) and fundus autofluorescence (FAF) in central serous chorioretinopathy (CSCR)
Methods : MCI and FAF images of clinically diagnosed cases of CSCR from two study sites were analysed. Six clinical findings – neurosensory detachment (NSD),subretinal deposits, retinal pigment epithelium (RPE) atrophy, RPE alterations, pigment epithelial detachments (PED) and pachyvessels were recorded using image J (NIH, Bethesda, USA). Quantitative analysis included number of lesions and cumulative area of the lesions while qualitative analysis included the presence or absence along with definition of the lesions.
Results : 25 eyes of 21 patients were evaluated. In comparison to FAF, MCI showed higher number as well as higher mean cumulative RPE atrophic areas (6.3±6.02vs5.7±5.7 mm2, p=0.046) and RPE alteration areas (14.05±10.3 vs 13.3±11.1, p=0.094). A similar trend was noted in the mean cumulative area of NSD (17.9±10.5vs16.5±9.8 mm2, p=0.035) and PED (1.3±1.4vs1.1±1.2 mm2, p=0.068). MCI demonstrated NSD, PED and pachyvessels in more number of eyes in comparison to FAF while both investigations revealed sub retinal deposits, RPE atrophy and RPE alterations in equal number of eyes. Both investigations had a 100% sensitivity in detecting NSD and 100% specificity for sub retinal deposits.
Conclusion : MCI showed superiority compared to FAF, both qualitatively as well as quantitatively in characterizing the various clinical features of CSCR. MCI can be imaging modality of choice in documenting and monitoring structural changes in eyes with CSCR.
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