|
목적 : To evaluate the effectiveness and safety of treating choroidal melanoma and cancer metastasized to the choroid with gamma knife radiosurgery (GKS).
방법 : Between January 2007 and January 2018, nine patients who had intraocular tumors and who underwent GKS with a minimum follow-up of 1 month were included in this retrospective study. Eleven eyes of 9 patients with intraocular tumor were treated with GKS. The group of intraocular tumor consisted of 7 choroidal metastasis and 4 choroidal melanoma.
결과 : Their mean age at treatment was 56.8 ± 14.3 years (range, 32-83 years). The follow-up period after GKS was 6.7 ± 4.6 months (range, 1-13 months). The mean cumulative marginal dose was 26.2 ± 6.7 Gy (22-45 Gy). During the follow-up period, MRI revealed a decrease of tumor volume in 7 patients with symptomatic improvement.. Both eyes in one patient, tumor volume increased and a new choroidal lesion was not observed. Four of 7 patients reported subjectively improved visual symptom, but ocular pain was relieved. Although tumor regression, one patient had worse visual acuity.
결론 : When relatively high doses of radiation and longer treatment period in external beam radiotherapy were taken into account, GKS was shown to be safe and effective for choroidal lesions and might play a major role or even be substituted for conventional radiotherapies.
|