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목적 : To investigate the association between autonomic dysfunction and posterior scleral profile in normal tension glaucoma
방법 : Posterior scleral profile, which was identified by the disc tilt ratio, disc torsion, disc foveo angle and ratio of peripapapillary area(PPA) to disc area, was measured from disc photographs. Patients were classified into the two groups according to the standard deviation value of the qualified normal to normal intervals(SDNN) of the heart-rate-variability assessment.Two groups were compared. Logistic regression analysis was used to determine the relationship between posterior scleral profile and abnormality of heart rate variability.
결과 : Group1 had a SDNN values between 15.55 and 51.87 and Group 2 had a SDNN value less than 15.55 or greater than 51.87. Among 208 NTG eyes, 164(78.8%) were group 1 and 44(21.2%) were group 2. Axial length was significantly longer in Group 2 than Group 1(p=0.008). Degree of disc torsion were significantily higher in Group 2 than group 1(p<0.001). Although just short of statistical significance(p=0.058), disc tilt ratio was higher in group 2. Torsion degree was the only factor related to heart rate variability in both univariate (p <0.001) and multivariate (p=0.008) logistic regression analyses.
결론 : Our study results showed that the dysfunction of an autonomic control is associated with posterior scleral profile such like disc tilt ratio, torsion degree, axial length.
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