|
Purpose : To determine prognostic factors associated with the successful treatment in ocular tuberculosis patients.
Methods : A 5-year retrospective cross-sectional study. Patients with presumed or definite ocular tuberculosis were reviewed and evaluated demographics, host status, history of tuberculosis exposure, extraocular tuberculosis, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Tuberculin skin test (TST), QuantiFERON (QFT), chest radiology abnormalities, initial visual acuity(VA), ocular findings, Optical coherence tomography (OCT), Fluorescein Angiography (FFA) findings, time from diagnosis to treatment, duration of treatment and treatment options.
Results : Total of 51 patients (77eyes) with presumed or definite ocular tuberculosis who had successful outcome 74 eyes (96.1%). Patients with successful treatment had initial VA ≥ 20/200 (53 eyes, 71.6%), ESR < 60 mm/hr. (47 patients, 92.16%), no complication from uveitis (51eyes, 68.92%) and no extraocular tuberculosis (42 patients, 82.35%). Any ocular findings included retinal vasculitis, choroiditis, retinitis, papillitis and choroidal granuloma were not significantly associated with treatment outcome.
Conclusion : Patients with initial VA ≥ 20/200 and ESR < 60 mm/hr. were associated with successful treatment in case ocular tuberculosis, whereas patients with HIV infection, extraocular tuberculosis and complication of uveitis; retinal detachment, were associated with failure treatment.
|