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Purpose : This study aims at 1- clinical features of a series of AOLP cases which are hard to diagnose, 2- comment on anatomohistology of those cases.
Methods : A series cases study, 32 patients suffering AOLP, with difficulty in anatomohistology diagnosis.
Results : Average age: 56, male dominated, mostly suffer unilateral eye (68%). Causes of hospitalisation: mass palpations, eye lids edema, ptosis. Visual acuity good > 90%, IOP normal except cases combined with glaucoma.
6 patients (19%) need immunohistochemistry analysis for sub-type group classification. The conflicts in anatomohistologic analysis are found mainly in EMZL( Extranodal Marginal Zone Lymphoma)group. These immuno markers CD20, CD79a, CD10, CD5, CD23, Bcl-2, Bcl-6, Cyclin D1, IgG light chain... are useful in sub-type classification.
Conclusion : There are no clinical criteria, standard X-ray for the diagnosis of disease of AOLP. Without immunohistochemistry analysis it is not possible to identify the right and wrong for atypical cases. So immunohistochemistry analysis is the most useful tool to diagnose the nature of the disease
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