| 발표일자: |
2019년 4월 5일(금)~7(일) |
| 발표번호: |
P-003 |
| 발표장소: |
벡스코 전시장 1홀 내 |
|
|
| 점안 프로스타글란딘 제제 사용과 연관된 Meibomian gland의 형태학적 변화 평가 방법으로서의 Meibomian gland dropout rate |
| 연세대학교 의과대학 안과학교실 시기능 개발 연구소 |
| 김주연, 이상엽, 최웅락, 이광현, 배형원, 성공제, 김찬윤 |
|
목적 : This study assessed the clinical usefulness of meibomian gland (MG) dropout rate in glaucoma patients using prostaglandin analogues by investigating the association between morphologic alterations in the MG and the MG dropout rate in Tafluprost users
방법 : This cross-sectional study was conducted on 88 eyes of 88 patients who were diagnosed with glaucoma and used only Tafluprost as treatment. The patients were divided into four “user” groups: 1) 23 patients used preservative-free (PF) Tafluprost for 6 months; 2) 21 patients used preservative-containing (PC) Tafluprost for 6 months; 3) 23 patients used PF-Tafluprost for 24 months; 4) 21 patients used PC-Tafluprost for 24 months. Examinations of the ocular surface and MG condition, including MG dropout rate and meiboscale, were performed on these patients.
결과 : MG dropout rate and meiboscale showed significant differences in all post hoc analyses, except for the comparison between PF and PC-Tafluprost 6-month user groups. Medication duration, preservative status, and meiboscale were significantly correlated with MG dropout rate (p<0.001, p=0.024, p<0.001, respectively). In the 6-month user group, preservative status significantly correlated with MG dropout rate (p=0.015). However, in the 24-month user group, meiboscale was the only parameter significantly associated with MG dropout rate (p<0.001).
결론 : MG dropout rate in patients using Tafluprost showed a significant correlation with medication duration and preservative status.
|
| |