| UV F-006 |
| Choroidal vascularity index and choroidal thickness in human leukocyte antigen-B27-associated uveitis |
| 1. Department of Ophthalmology and Visual Science, Seoul St.Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
2. Catholic Institute for Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea |
| Mirinae Kim(1), Young-Hoon Park(1,2) |
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목적 : To assess choroidal thicknesses and choroidal vascularity index (CVI) in HLA-B27-associated uveitis.
방법 : Medical records of 45 treatment-naive unilateral HLA-B27-associated uveitis patients presenting with their first episode and with an onset time of < 1 week were retrospectively reviewed. Optical coherence tomography (OCT) was conducted at initial visitation and after uveitis resolution. Follow-up OCT was conducted after periods of inactivity without treatment of ≥ 3 months.
결과 : Mean choroidal thickness was 275.98 ± 71.62 in acute phase and 254.93 ± 73.48 after resolution (P = .003). Mean CVI was 34.75 ± 3.08 in acute phase and 33.56 ± 2.48 after resolution (P < .001). Interestingly, even in fellow eyes, there were relative retinal and choroidal thickening and relative choroidal vascular engorgement in acute phase, but these differences were not significant. Degree of anterior chamber inflammation was correlated with relative choroidal vascular engorgement (P = .001) and choroidal thickening (P = .044).
결론 : Eyes with acute HLA-B27-associated uveitis exhibited choroidal thickening with increased choroidal vascularity that subsequently decreased after uveitis resolution. These were evident even in patients without posterior segment involvement.
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