| GL F-032 |
| Progression Pattern of Initial Single Hemifield Defect in Glaucoma Patients: An 8-Year Mean Follow-Up Study |
| 1 Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea
2 Department of Ophthalmology, Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea
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| Sung Uk Baek1, Kyung Wha Lee2, Young Kook Kim1, Ki Ho Park1, Jin Wook Jeoung1 |
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목적 : To investigate clinical outcomes of primary open angle glaucoma (POAG) with an initial single hemifield defect in visual field (VF) test and its related risk factors for involving the opposite hemifield during follow-up (FU).
방법 : This longitudinal observational study included 108 POAG eyes of 108 patients that met the following conditions: 1) single hemifield defect at initial VF test; 2) FU longer than 5 years. Patients were divided into ‘Group A’ (sparing the opposite hemifield) and ‘Group B’ (involving the opposite hemifield) according to the patterns of VF progression. Baseline demographic and clinical characteristics were compared between the two groups. The Cox proportional hazards model was used to identify the risk factors for involving the opposite hemifield.
결과 : The average FU period was 7.9 years, and 63 eyes (58.3%) classified as Group A and 48 eyes (41.7%) did as Group B. Between two groups, no significant differences were found in the FU periods (7.8 vs. 8.0 years), baseline VF mean deviation (-9.67 vs. -10.06 dB), mean baseline IOP (17.21 vs. 16.87 mmHg), and percentage reduction in IOP (21.6 vs. 20.6 %) (all P <0.05). The multivariate Cox proportional hazards model indicated that older age (HR = 1.704; P = 0.025) and absence of optic disc vertical tilt (HR = 1.430; P = 0.017) were risk factors for involving the opposite hemifield.
결론 : In POAG with an initial single hemifield defect, 41.7% showed involving the opposite hemifield during the average 8.0-years of FU. The older age and absence of optic disc vertical tilt were significantly associated with greater probability for involving opposite hemifield.
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