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목적 : To evaluate the safety and efficacy (intraocular pressure [IOP] lowering effect and medication use) of a single trabecular microbypass stent (iStent®) for medically controlled open-angle glaucoma.
방법 : This retrospective case-series included 23 eyes of 18 patients with medically controlled open-angle glaucoma with IOP less than 18 mm Hg. Clinical outcomes analyzed IOP, medication use, corrected distance visual acuity (CDVA), and surgical complications. Surgical success was defined according to 3 different criteria: (1) IOP < 21 mmHg without medication; (2) IOP < 18mm Hg without medication; and (3) IOP < 18 mmHg with or without medication. Patients were followed for 6 months postoperatively.
결과 : At 6 months, mean IOP was reduced from 15.0±1.3 mmHg to 13.2±1.2 mmHg. Mean number of medication decreased from 2.17±1.07 to 0.52±0.9 (P<0.001). Surgical success rates were 87.0%, 73.9%, and 100% by Criteria 1,2,3. And 73.9% of patients were medication-free at 6 months. Relative risk of surgical failure (IOP<18 mmHg without med) was 5.56 times greater for the higher-medication group (med≥3). CDVA was significantly improved from 0.44±0.10 to 0.09±0.06 LogMAR in combined phacoemulsification and iStent® implantation group(P< 0.001). There was no vision threatening or severe complication.
결론 : Single trabecular microbypass stent implantation was effective in reducing IOP and medication in OAG with a low preoperative IOP. Further studies are needed to evaluate long-term outcomes in Korea.
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