| GL F-025 |
| Position of central retinal vascular trunk and preferential location of glaucomatous damage in myopic normal-tension glaucoma |
| 1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
2. Seoul National University Boramae Medical Center, Seoul, Korea
3. Department of Ophthalmology, Dongguk University Ilsan Hospital, Goyang, Korea |
| Kyoung Min Lee(1,2), Martha Kim(3), Sohee Oh(2), Seok Hwan Kim(1,2) |
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목적 : To investigate the spatial correlation between the central retinal vascular trunk and the preferential location of glaucomatous damage in myopic normal-tension glaucoma (NTG) eyes.
방법 : The position of the vascular trunk was measured from the center of the Bruch’s membrane opening (BMO), which was delineated by OCT imaging. The angular deviation was measured, with the horizontal nasal midline as 0° and the superior location as a positive value. The shift index was calculated as the distance of the vascular trunk from the BMO center relative to that of the BMO margin. The angular location of the midpoint of the retinal nerve fiber layer (RNFL) defect was measured from the BMO center. The vascular trunk position and the location of glaucomatous damage were compared.
결과 : The moderate- and severe-shift groups (shift index≥0.5) were associated with younger age, longer axial length, smaller angular deviation, and lesser incidence of focal LC defect. A multiple regression analysis showed a significant correlation between the vascular trunk position and the RNFL defect location (P<0.001). A logistic regression analysis revealed that the dominant RNFL defect occurred in the opposite hemisphere of the vascular trunk (P<0.001), and bi-equivalent involvement in both hemispheres was associated with larger shift index (P=0.001).
결론 : In myopic NTG eyes, the vascular trunk is located in the direction opposite to RNFL defect with reference to the BMO. Because the vascular trunk is embedded in the LC, this implies that LC shift during axial elongation is associated with greater vulnerability of myopic eyes to glaucomatous damage.
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