| GL F-004 |
| Topographic Correlation between Macular Superficial Microvessel Density and Ganglion Cell-Inner Plexiform Layer Thickness in Normal-Tension Glaucoma |
| ¹Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea
²Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea |
| Jin-Soo Kim¹, Young Kook Kim¹², Sung Uk Baek¹, Ahnul Ha¹², Yong Woo Kim¹, Jin Wook Jeoung¹², Ki Ho Park¹² |
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목적 : To investigate the topographic relationship between macular superficial microvessel density (SMD) and macular ganglion cell-inner plexiform layer (GCIPL) thickness in early-stage normal-tension glaucoma (NTG).
방법 : A total of 70 eyes of 70 patients with early NTG (standard automated perimetry mean deviation > -5.5 decibels) and a total of 9 eyes of 9 patients with preperimetric NTG underwent optical coherence tomography (OCT) and OCT angiography. On the OCT angiography scan image, macular SMD was analyzed by customized software.
결과 : Macular GCIPL thickness showed significant correlation with macular SMD in superotemporal (ST), inferotemporal (IT) and inferoinferior (II) sector (P = 0.020, 0.012, and 0.040, respectively). Between ST-IT and SS-II sector, the difference of GCIPL thickness was correlated with the difference of SMD as well (P < 0.001 and P = 0.004, respectively). In addition, circumpapillary retinal nerve fiber layer (RNFL) thickness and macular SMD showed significant correlation between ST sector of macula and 1, 9 clock-hour peripapillary region, and also between IT and II sector and 7, 8 clock-hour region.
결론 : Sectorial macular SMD showed topographic correlation with macular GCIPL thickness and circumpapillary RNFL thickness in patients with early-stage NTG. Macular SMD analysis can be potentially useful in the clinical evaluation of early glaucoma.
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