| GL F-002 |
| Effect of Optic Disc Size on Bruch’s Membrane Opening-Minimum Rim Width and Peripapillary Retinal Nerve Fiber Layer Thickness |
| 1Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Gyeongsang National University, School of Medicine, Changwon, Republic of Korea, 2lnstitute of Health Sciences, School of Medicine, Gyeongsang National University, Jinju, Republic of Korea, 3Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea |
| Hyun-kyung Cho, MD, PhD,1,2 Jong Moon Park, MD, PhD,1,2 Changwon Kee, MD, PhD3 |
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목적 : To investigate the effect of optic disc size on Bruch’s membrane opening minimum rim width (BMO-MRW) and peripapillary retinal nerve fiber layer (RNFL) thickness, we evaluated BMO-MRW and RNFL thickness from three different scan circle sizes according to optic disc size and also inspected the correlations between them.
방법 : In this retrospective, observational study, non-glaucomatous eyes with no visible RNFL defect and no visual field loss were included. One hundred and one subjects were distributed into three groups regarding disc size: group 1(n=26), small disc (disc area<1.63 mm2); group 2(n=40), regular size disc (disc area: 1.63 ~ 2.43 mm2); group 3(n= 35), large disc (disc area>2.43 mm2). The patients underwent standard ophthalmic examinations including confocal scanning laser tomography and Spectralis spectral-domain optical coherence tomography.
결과 : Global BMO-MRW was the thickest in group 1(314.96±60.38 um), followed by group 2(259.03±40.04 um), and the thinnest in group 3(236.74±31.21 um; P <0.001, Kruskal-Wallis test). Correlation between global BMO-MRW values and RNFL thickness was the strongest in group 3(Spearman’s rho=0.656), followed by group 2(rho=0.572), and none in group 1(rho=0.147). No significant differences were found in global RNFL thickness by disc size in either the 3.5 mm, 4.1 mm, or 4.7 mm diameter scan circles (all P >0.05).
결론 : BMO-MRW differed significantly according to disc size. Correlation between BMO-MRW values and RNFL thickness may also vary according to disc size. When we assess the new parameter BMO-MRW in relation to RNFL thickness, disc size may need to be taken into consideration.
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