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목적 : Drusen in pachychoroid disorders show certain differences from conventional drusen and are recently named as ‘pachydrusen’. This study analyzed the specific choroidal morphology under pachydrusen.
방법 : The presence of pachydrusen in fundus area covered by a 12x9 mm2 optical coherence tomography (OCT) image was accessed in eyes with pachychoroidrelated diseases using colour fundus photography and swept source OCT. Choroidal morphology under the pachydrusen was analyzed using OCT B scans and en face images.
결과 : A total of 225 pachydrusen in 136 eyes were analyzed. The mean number of pachydrusen was 1.65±1.07 per eye. Most pachydrusen were located para or perifoveally (37 subfoveal, 86 parafoveal, and 102 perifoveal). The proportion of Haller’s layer to total choroidal thickness was higher at the area of the pachydrusen compared to the subfovea (0.881±0.081 vs. 0.765±0.111, p < 0.001). In multimodal image analysis, 90.1% of pachydrusen identified using fundus photography and OCT Bscan were located at the area of a dilated Haller vessel (pachyvessel) seen on en face images.
결론 : Choroidal morphology under the pachydrusen showed increased Haller’s layer thickness with an attenuated choriocapillaris layer, which is the hallmark of pachychoroid definition. Topographically, their locations correlated with the underlying pachyvessel.
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