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목적 : To evaluate the age-related difference in the incidence of the subtypes of newly diagnosed neovascular age-related macular degeneration (AMD).
방법 : This retrospective, observational study included 1099 eyes of 1099 patients diagnosed with neovascular AMD. The neovascular AMD cases were classified into 3 subtypes: typical neovascular AMD, polypoidal choroidal vasculopathy (PCV), and type 3 neovascularization. The patients were divided into 4 groups, according to age: >50 and <60 years, ≥60 and <70 years, ≥70 and <80 years, and ≥80 years. Difference in the incidence of 3 AMD subtypes was evaluated among the 4 age groups.
결과 : In the age group >50 and <60 years, 34 (25.0%) and 102 patients (75.0%) were diagnosed with typical neovascular AMD and PCV, respectively. In the age group ≥60 and <70 years, 90 (28.1%), 206 (64.4%), and 24 patients (7.5%) were diagnosed with typical neovascular AMD, PCV, and type 3 neovascularization, respectively. In the age group ≥70 and <80 years, the corresponding numbers were 200 (41.9%), 197 (41.3%), and 80 (16.8%), respectively; in the age group ≥80 years, the corresponding values were 83 (50.0%), 39 (23.5%), and 44 (26.5%), respectively.
결론 : The incidence of the subtypes of newly diagnosed neovascular AMD differs according to age. This result suggests that a different pathophysiology may be involved in the development of different subtypes of neovascular AMD.
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