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목적 : To investigate the factors associated with glaucoma in patients with pseudoexfoliation sysdrome by comparing features of the anterior segments and ocular biometry according to the presence or absence of open angle glaucoma in pseudoexfoliation syndrome.
방법 : We analyzed 96 patients (115 eyes) diagnosed as pseudoexfoliation syndrome in this study. We divided them into two groups of simple pseudoexfoliation syndrome (64 patients 76 eyes) and pseudoexfoliation glaucoma (32 patients 39 eyes). We compared the age, sex, underlying disease, location of pseudoexfoliative material, changes of iris, degree of nuclear cataract, pupil dilatation, corneal endothelial cell counts, central corneal thickness, anterior chamber depth, axial length, and IOP.
결과 : There were no significant differences between the two groups in age (p = 0.694), sex (p = 0.161), DM (p = 0.440), HTN (P = 0.238), pseudoexfoliative material observed in anterior capsule, pupillary margin (p=0.700, and 0.210), iris depigmentation (p=0.526), pupillary ruff loss (p=0.708), the degree of nuclear cataract (p=0.617), pupil dilatation (p=0.526), CCT (p = 0.097), ACD (p = 0.283), AL (p = 0.095). In pseudoexfoliation glaucoama, significantly high IOP (p=0.026), high frequency of membrane formation (p=0.047), and decreased coneal endothelial cell counts (p=0.048) were observed.
결론 : Pseudoexfoliation syndrome with open angle glaucoma was shown to be associated with high IOP, decreased corneal endothelial cell counts, and high frequency of membrane formation. Therefore, when such changes are observed in pseudoexfoliation syndrome patients, higher risk of open angle glaucoma should be recognized and careful attention need to be paid accordingly.
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