| 본문 : Backgrounds and aims : It is difficult to differentiate between retinal astrocytic hamartoma and retinoblastoma. We report an infant with tuberous sclerosis who was considered to have retinoblastoma clinically.
Methods and Results : An 3-month-old infant with tuberous sclerosis was referred with retinal tumors in the posterior poles of both eyes. His family history was unremarkable. Anterior segment of both eyes were normal. Fundus examination showed 4-disc-diameter gray-whitish elevated mass in the posterior pole of the right eye and multiple small fleck-like lesions in the both eyes. Repeated examinations revealed small new retinal lesions that appeared to enlarge gradually. Although tuberous sclerosis was reminiscent of retinal astrocytic hamartoma, white, opaque, elevated main mass and the presence of tumor enlargement raised concern for retinoblastoma clinically. Transpupillary thermotherapy was applied to lesions in the both eyes several times. Fundus appearance remains unchanged for 6 months since his last treatment.
Conclusion : Although retinal astrocytic hamartomas are common in tuberous sclerosis, retinoblastoma should be considered in atypical retinal mass in infant with tuberous sclerosis. Local treatment might be beneficial before enlargement and aggravation of retinal mass. |