|
목적 : To compare the progression of glaucoma between unilateral disc hemorrhage (DH) group and bilateral DH group and demonstrate the associated risk factors.
방법 : A total of 78 bilateral primary-open angle glaucoma patients (48 eyes in unilateral DH group and 30 eyes in bilateral DH group) were included. Glaucoma progression was defined by visual field (VF) deterioration. The mean VF global indices progression rates in pre-DH, post-DH, and total follow-up period were compared between the two groups. The cumulative probability of glaucoma non-progression between the two groups was compared by Kaplan–Meier survival analysis. Multivariate Cox’s proportional hazard model were used to identify the risk factors for glaucoma progression.
결과 : Among the mean VF global indices progression rates, only the mean PSD progression rate between unilateral DH and bilateral DH group showed statistically significant difference (unilateral DH group; 0.30±0.38 dB/years, bilateral DH group; 0.13±0.27 dB/years) (P = 0.042). The Kaplan–Meier analysis revealed a greater cumulative probability of non-progression for the bilateral DH group than for the unilateral DH group (P = 0.008). Multivariate Cox’s proportional hazard model indicated that unilaterality of DH was a factor associated with glaucoma progression (HR = 2.587, P = 0.030).
결론 : Unilateral DH eyes in bilateral POAG patients were associated with glaucoma progression than bilateral DH eyes in bilateral POAG patients. Unilateral DH eyes in bilateral POAG patients should undergo careful and frequent follow up and consideration should be given to more aggressive treatment.
|