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목적 : We subdivided high myopia with cluster analysis using disc and posterior scleral parameters to compare the presence of open-angle glaucoma (OAG) of clustered groups.
방법 : A total of 96 high myopic eyes were enrolled in this cross-sectional study; 48 glaucoma patients with high myopia (HM-G) and 48 high-myopia controls (HM-C). Patients underwent swept-source optical coherence tomography (SS-OCT) scans to measure peripapillary RNFL thickness, disc, and posterior scleral parameters. We classified high myopia into homogenous subgroups based on these variables using a cluster analysis, and compared clusters to evaluate diverse characteristics and the presence of OAG.
결과 : Five clusters were found after factor analysis. Cluster 1 (12 eyes) had the widest peripapillary atrophy (PPA) area. Cluster 2 (28 eyes) was characterized by the thin subfoveal sclera thickness and large disc-foveal angle. Cluster 3 (20 eyes) had largest disc tilt ratio and pointed posterior scleral contour. Cluster 4 (20 eyes) had largest disc torsion degree, and Cluster 5 (16 eyes) had high IOP. Cluster 3 had the highest number of OAG patients (p < 0.05).
결론 : A cluster analysis divided high myopia into 5 groups based upon disc and posterior scleral parameters. There was a high presence of OAG in eyes with high myopia showing large disc tilting ratio and pointed posterior sclera contour.
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