| 정재림¹, 고경민¹, 김국영¹, 권영아¹, 송상률¹, 김병엽¹, 김나현², 염형선², 김현창² |
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목적 : To evaluate high sodium intake as a risk factor for dry eye disease in a Korean rural population.
방법 : A cross-sectional study was performed for 17,476 people, using data from 2010-2011 Korea National Health and Nutrition Examination Survey. We excluded participants not performing the questionnaire for dry eye, under 19 years old, having higher blood creatinine (> 1.2 mg/dl), having cardio-cerebrovascular disease, liver disease, cancer, taking eye surgery, taking antihypertensive drugs, and kidney disease. Dietary sodium intake was estimated using urinary sodium to creatinine ratio (U[Na+]/Cr). Dry eye was measured by the diagnosis of ophthalmologist.
결과 : Among a total 6,488 participants, 497 (7.7%) was diagnosed dry eye. Men with dry eye had significantly higher U [Na+]/Cr than those without dry eye (p =0.018). However, there was no difference of U [Na+]/Cr between women with dry eye and those without dry eye (p= 0.245). When performing sex-specific analysis, odds ratio [OR] (95% confidence interval [CI]) for dry eye increase in U[Na+]/Cr in men was 1.02 (1.01-1.04). However, increasing U [Na+]/Cr was not significantly related to dry eye diagnosis in women (OR 1.00, 95% CI 0.99-1.00) and it did not change after adjusting for covariates.
결론 : Increasing U [Na+]/Cr was significantly associated with dry eye disease in men, whereas, it was not related to dry eye in women.
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