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목적 : To determine refractive errors and anatomical outcomes associated with laser photocoagulation (PRP) versus intravitreal bevacizumab (IVB) when treating type 1 retinopathy of prematurity (ROP) in zone 2.
방법 : Consecutive infants with type 1 ROP who received either IVB or PRP for type 1 ROP between 2006 and 2013 were reviewed from 2 tertiary referral hospitals. Recurrence rate, complication rate, refractive error and anatomical outcomes were compared between the two groups.
결과 : A total of 156 eyes (79 patients) with type 1 ROP were evaluated and those treated for zone 2 abnormalities were specified (n=115 eyes). 56 eyes received PRP only, 49 received IVB only, and 10 received combination. Mean gestational age, birth weight, postmenstrual age, and follow-up period for infants receiving PRP or IVB only were compared. Recurrence was noted in 11 eyes (9.57%) with the majority after IVB only (p<0.001). Mean spherical equivalence were +0.25 diopters (D) or PRP only and +0.43 D for IVB-treated eyes.
결론 : Both IVB and PRP are effective treatment options for type 1 zone 2 ROP with similar refractive and anatomical outcomes. For concerns of late tractional detachment and recurrence for infants receiving IVB only, laser treatment can be considered more favorably in type 1 ROP of zone 2.
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