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목적 : To compare the patterns of retinal ganglion cell damage, peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell plus inner plexiform layer (mGCIPL), between primary open-angle glaucoma (POAG) and nonarteritic anterior ischemic optic neuropathy (NAION).
방법 : Thirty eyes of 30 patients with unilateral NAION and their age-, sex- and average pRNFL thickness matched 90 eyes with 90 patients with POAG were enrolled in this study. All of the patients underwent thorough eye examination including spectral domain optical coherence tomography. Average and sectoral thickness of the pRNFL and mGCIPL were compared between NAION and POAG.
결과 : The pRNFL thickness of the 1 and 2 o’clock (superonasal) area in NAION was significantly thinner than that in POAG (65.5 ± 16.8 and 76.4 ± 22.1 μm, p = 0.015, 59.7 ± 14.8 and 75.9 ± 17.5 μm, p = 0.044, respectively). The pRNFL thickness of 7 o’clock (inferotemporal) area in POAG was significantly thinner than that in NAION (75.3 ±30.6 and 93.1± 38.6 μm, p = 0.010). The mGCIPL thickness of the superotmporal, superior, superonasal, and inferonasal sector in NAION was significantly thinner compared to POAG (all p < 0.05).
결론 : The pRNFL thickness of the superonasal sector in NAION was thinner than POAG. The pRNFL thickness of the inferotemporal sector in POAG was thinner than NAION. The sectoral mGCIPL thickness in NAION was thinner POAG except inferior and inferotemporal sectors in which there are no differences between NAION and POAG.
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