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목적 : Periodontal disease (PD) is associated with various systemic diseases.
We investigated the association between PD and age-related macular degeneration
(AMD).
방법 : For this population-based, cross-sectional study, we enrolled 13,072 adults
at least 40 years of age with gradable retinal fundus photographs and community
periodontal index (CPI) data from the Korean National Health and Nutrition
Examination Survey (KNHANES) (2008-2010 & 2012). Participants were divided into a
middle age group (age ≤ 60 years) and old age group (age > 62 years)). PD was
divided into two categories of mild and severe. Logistic regression analysis was used
to evaluate the association between PD and AMD (early and late).
결과 : The prevalence of PD, AMD in the study population was 37.4±0.8 and
5.6±0.2%, respectively. there was no significant difference in the proportion
of participants with PD between those with and without AMD. Only participants with
AMD in the middle age had more any PD than those without AMD (P=0.031).
Multivariate logistic regression after adjusting for all confounding factors showed
that PD was not significantly associated with AMD(OR1.03, 95%CI 0.86-1.22).
However, according to degree of PD, participants with severe PD in the middle age
group were 1.61 times more likely to have AMD(95%CI 1.02-2.54).
결론 : Our data, collected from an Asian population, showed that only severe
PD is independently associated with AMD in individuals aged 62 years or younger.
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