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목적 : To measure the thickness of all ten retinal layers by using the Spectral-domain optical coherence tomography(SD-OCT) and analyze the effect of age, sex and axial length on retinal thickness in high myopic patients and non-high myopic patients.
방법 : 378 eyes from 378 patients who didn’t have any kind of ocular disease were reviewed and their individual ten retinal layer thickness was measured using SD-OCT automated retinal layer segmentation program. According to axial length (26mm), all eyes were divided into two groups: high myopic group (group A) and non-high myopic group (group B). The primary outcome measure was the thickness of each retinal layers.
결과 : In group A, the thickness of center subfield of total retinal layer(TRL), retinal nerve fiber layer(RNFL), ganglion cell layer(GCL), inner nuclear layer(INL) and outer plexiform layer(OPL) were significantly thicker compared to those of group B. With the group B, the center of all retinal layers were thicker in men compared to women except in the OPL, photoreceptor layer and retinal pigment epithelium(RPE). In group B, TRL, RNFL, GCL and IPL decreased significantly with increasing age in most of the subfields but in group A, only RPE show significant correlation with increasing age.
결론 : According to high myopic and non-high myopic status, effects of age sex and axial length on thickness of ten retinal layers were different and these effects should be taken into consideration when evaluating changes of individual retinal thickness in various macular diseases.
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