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목적 : To analyze the correlation between microperimetry and multifocal electroretinography (mfERG) in idiopathic epiretinal membrane (ERM).
방법 : This retrospective study examined 33 patients with unilateral ERM who had undergone microperimetry and mfERG. Normal fellow eyes of the same patients were included to provide normative values for each test. The mean retinal sensitivity in microperimetry and the mean N1-P1 response amplitude and P1 implicit time on mfERG were compared between the eyes with ERM and the fellow eyes. Correlations were analyzed between retinal sensitivity and mfERG parameters in eyes with ERM.
결과 : For the average of all points, microperimetric retinal sensitivity was significantly lower (P = 0.001) in the eyes with ERM, but mfERG N1 to P1 response amplitude and P1 implicit time was not significantly different (P = 0.605 and P = 0.634, respectively) in the eyes with ERM compared to those in the fellow eyes. Considering retinotopically matched points, there was significant correlation between the average Z-scores of the microperimetric retinal sensitivity and mfERG response amplitudes (correlation coefficient, R = 0.492, P = 0.028), or implicit time (R = -0.451, P = 0.046).
결론 : Microperimetric retinal sensitivity was correlated with mfERG response amplitude and implicit time in ERM. Microperimetry might be sensitive enough to identify subtle retinal functional changes associated with ERM before mfERG parameters are significantly changed.
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