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목적 : To describe the clinical and imaging characteristics of the peripapillary retinoschisis in eyes with pachychoroid-related diseases.
방법 : The medical records of 12 patients (12 eyes) were reviewed. Findings from
enhanced-depth imaging (EDI) of the Spectralis optical coherence tomography (OCT) including lamina cribrosa (LC), fluorescein angiography (FA) and clinical course were analyzed.
결과 : Among 12 eyes, 10 had chronic central CSC, one had PED, and one had PCV. LC abnormalities, peripheral LC disinsertions in 5 eyes and peripheral LC defects in one eye, were noted on EDI imaging of the optic nerve head (ONH). FA revealed late leakage at the temporal β zone of ONH in 9 eyes. Peripapillary retinoschisis showed partial or complete resolution after intravitreal injection of ranibizumab or aflibercept in 6 eyes, and after photodynamic therapy in 1 eye. In 3 eyes treated with focal photocoagulation for chronic CSC, retinoschisis remained after the resolution of subretinal fluid.
결론 : Peripapillary retinoschisis is found in eyes with pachychoroid-related retinal diseases. Thickened choroid and increased hydrostatic pressure within the choroid may result in alterations in the LC or the temporal β zone of ONH. This suggests that the source of intraretinal fluid is the subarachnoid space of choroid.
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