| 발표일자: |
2016년 4월 9일(토) 10:00 ~ 4월 10일(일) |
| 발표번호: |
P(e-poster)-037 |
| 발표장소: |
킨텍스 제2전시장 7B홀 |
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| 공급 혈관을 가진 결절맥락막혈관병증: 특징, 반대안의 소견 및 장기간 유리체강내 항혈관내피세포성장인자 주사 치료의 결과 |
| 건양대학교 의과대학 김안과병원 안과학교실 명곡안연구소 |
| 이관복, 김종우, 김철구, 이동원, 유수진, 김재휘 |
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목적 : To evaluate the long-term outcomes of anti-vascular endothelial growth factor (VEGF) therapy for polypoidal choroidal vasculopathy (PCV) with feeder vessels and to investigate fellow-eye findings.
방법 : This retrospective observational study included 14 eyes with treatment-naïve PCV accompanied by feeder vessels that were treated with anti-VEGF monotherapy. The best-corrected visual acuity (BCVA) at baseline was compared with that at the last follow-up. The fellow-eye indocyanine green angiography (ICGA) findings were also analyzed.
결과 : The mean follow-up period was 28.1 ± 19.2 months. During the follow-up period, 5.9 ± 2.5 anti-VEGF injections were administered. Although the BCVA at the last follow-up was not different from the baseline value (P = 0.809), an improvement of ≥0.2 logMAR BCVA was observed in seven eyes. In 11 eyes that underwent bilateral ICGA at diagnosis, PCV, branching vascular networks, and late geographic hyperfluorescence were noted in two, five, and three fellow eyes, respectively. During the follow-up period, the development of polypoidal lesions in the fellow eye was observed in three patients.
결론 : In this study, long-term improvement in BCVA was noted in 50% of the included patients who received anti-VEGF monotherapy. A relatively high incidence of pathological findings in the fellow eye and bilateral involvement suggest the need for bilateral examinations.
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