| 녹F-042 |
| 생분해성 콜라겐 매트릭스를 이용한 아메드 방수유출장치 삽입술 후 여과포 분석과 단기 결과 ; 6개월 관찰 |
| 1차의과학대학교 분당차병원 안과학교실, 2제일안과, 3동아대학교 의과대학 안과학교실, 4연세대학교 의과대학 시과학연구소 |
| 이상민1, 마경탁2, 노세현3, 김찬윤4, 노승수1 |
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목적 : To evaluate the short-term efficacy of a biodegradable collagen matrix (BCM) as an adjuvant for Ahmed valve implantation surgery to prevent the hypertensive phase.
방법 : This prospective study included 43 refractory glaucoma eyes all followed for 6 months. Refractory glaucoma was defined as an IOP >20 mmHg with anti-glaucoma eye drops without previous surgery. Conventional method was performed in 21 eyes and BCM-augmented Ahmed valve implantation (BAAVI) in 22 eyes. In the BAAVI group, a 10x10x2-mm BCM was sutured on an Ahmed glaucoma valve FP7 model. Complete success was defined as an IOP ≤21 mmHg and qualified success as an IOP ≤21 mmHg with or without medications. Maximal bleb thickness was measured using AS-OCT images
결과 : The preoperative IOPs and numbers of preoperative anti-glaucoma medications were similar for both groups. Complete success rates were 38.1% and 86.4% and qualified success rates were 52.4% and 90.9% in the conventional and BAAVI groups, respectively (p<0.05). The hypertensive phase rate was lower in the BAAVI group (4.5% vs. 47.6%, p=0.002). Maximal bleb thickness was increased in the BAAVI group on postoperative day 30 and 180 (p<0.05).
결론 : Success rates were higher in the BAAVI group than in the conventional group with the change of bleb morphology. Furthermore, use of BCM significantly decreased the need for anti-glaucoma medications for at least 6 months postoperatively.
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