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목적 : To investigate the relationship between corneal deformation amplitude and posterior pole profiles including β-zone parapapillary atrophy, optic disc tilt ratio, torsion degree, and disc-foveal angle, in patients with glaucoma.
방법 : This retrospective study included 107 glaucoma patients. Each patient underwent measurement of deformation amplitude with Corvis ST, color optic disc photography, red-free retinal nerve fiber layer photography, axial length measurement, and SITA 24 2. From fundus photos, beta zone parapapillary atrophy area, optic disc tilt ratio, torsion degree, and disc-foveal angle were obtained. Relationship between deformation amplitude and posterior pole profiles were determined
결과 : Mean tilt ratio, torsion degree, and disc-foveal angle were 1.16 ± 0.14, 10.26 ± 7.63 degrees, 7.60 ± 3.64 degrees, respectively. Mean PPA area was 18211.00 ± 28725.53 pixels. βPPA (r = 0.313, P = 0.008) and tilt ratio (r = 0.299, P = 0.002) had significant relationship with deformation amplitude. Torsion degree and disc-foveal angle showed no significant relationship with deformation amplitude. βPPA area was predicted by deformation amplitude(P=0.006) and axial length(P=0.005), and tilt ratio was predicted by axial length (P=0.001).
결론 : Deformation amplitude is related with PPA area and tilt ratio. This implies that corneal deformation amplitude could be a surrogate for increased deformability and susceptibility to glaucomatous damage of the optic nerve head.
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