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목적 : To propose a novel prognostic feature of spectral domain-optical coherence tomography (SD-OCT) in macula-involving branch retinal artery occlusion (BRAO).
방법 : We analyzed 66 eyes diagnosed with acute BRAO involving the macula. At the first visit, a detailed ophthalmic and medical history was obtained from all patients, and all underwent a comprehensive ophthalmic evaluation, which included visual acuity examination, fundus photography, fluorescein angiography, and SD-OCT. The same ophthalmic evaluation was performed at each follow-up visit. Analysis of retinal structure, including the papillomacular bundle (PMB) and the central minimal foveal thickness, using SD-OCT and its correlation with visual outcome were main outcome measures.
결과 : A total of 66 eyes were divided into 2 groups according to initial vision: Good Vision (≥ 20/40, 29 eyes, 44%) and Poor Vision (< 20/40, 37 eyes, 56%). The Poor Vision was further divided into Improvement (18 eyes, 27%) and Non-Improvement (19 eyes, 28%), according to visual recovery at the final exam. Among multiple OCT parameters, the involvement of PMB, but not that of the central fovea, was consistently observed in the Poor Vision (P < 0.001) and more significantly in the Non-Improvement (P < 0.001). Loss of layer-by-layer integrity was seen consistently in the Non-Improvement group.
결론 : In eyes with macula-involving BRAO, ischemic injury of the PMB at the acute stage, as seen on OCT, correlates closely with poor vision and can explain the poor visual prognosis.
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