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목적 : Inner retinal cleavage can be misdiagnosed as a glaucomatous retinal nerve fiber layer (RNFL) defect. This study was performed to characterize eyes with inner retinal cleavage.
방법 : Inner retinal cleavage is defined as the appearance of a dark spindle-shaped space between the nerve fibers. Consecutive patients who presented at our institution with inner retinal cleavage were enrolled in the study. All participants were evaluated by fundus examination, visual field testing with standard automated perimetry, and optical coherence tomography (OCT) imaging.
결과 : A total of 15 eyes of 11 subjects with inner retinal cleavage were included in the study. In each case, inner retinal cleavage was located adjacent to retinal blood vessels. Six eyes had epiretinal membrane (ERM), 2 eyes had glaucoma, and 1 eye had ERM as well as glaucoma. Six eyes with inner retinal cleavage without combined ocular abnormalities had highly myopic refractive error (-6.50 to -8.50 diopters) without visual field defects. Cross-sectional OCT images of the areas of inner retinal cleavage demonstrated defects with irregular margins and empty spaces in inner layers of the retina.
결론 : Inner retinal cleavage was found in eyes with high myopia or ERM. Inner retinal cleavage was associated with structural changes distinct from those associated with glaucomatous RNFL defects.
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