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목적 : To investigate the characteristics of macular ganglion cell-inner plexiform layer (GCIPL) thickness profiles associated with ocular dominance.
방법 : Participants were imaged by spectral-domain optical coherence tomography, and underwent dominant eye testing using a hole-in-a-card test (sighting dominance) at the same visit. Macular GCIPL, as well as circumpapillary retinal nerve fiber layer (RNFL) thickness were compared for individual patients, according to ocular dominance.
결과 : Ocular dominance occurred predominantly in the right eye (right vs. left: 72.36 vs. 27.60%; P < 0.001). Dominant eyes had significantly thicker average, temporal, and nasal RNFL thickness (P = 0.007, <0.001, and 0.008, respectively), whereas non-dominant eyes had significantly thicker superior RNFL thickness compared to dominant eyes (P = 0.036). In the comparison of macular GCIPL thickness, dominant eyes accompanied significantly thicker average, inferonasal, and inferior sectors compared to non-dominant eyes (P = 0.040, 0.005, and 0.032, respectively). Significant predictors of average GCIPL thickness were spherical equivalent (β = 1.37, P < 0.001), astigmatic power (β = 1.44, P = 0.009), disc area (β = 3.90, P < 0.001), average RNFL thickness (β = 0.22, P < 0.001), average cup-to-disc ratio (β = 5.74, P = 0.002), difference between the inferior and superior quadrant RNFL thicknesses (β = 0.08, P = 0.024), and ocular dominance (β = 2.10, P = 0.020). On multivariate regression analysis, ocular dominance was correlated with average GCIPL thickness after adjusting for potential confounders (P = 0.016).
결론 : Dominant eyes accompanied significantly thicker average macular GCIPL. This is the first reported study to demonstrate the macular GCIPL characteristics associated with ocular dominance. This information suggests that ganglion cell distribution in the macular area differs according to ocular dominance.
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