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목적 : To compare lesion characteristics between blue-light (488 nm) and green-light (532 nm) confocal scanning laser ophthalmoscopy (cSLO) autofluorescence (AF) of central serous chorioretinopathy (CSC).
방법 : The lesion characteristics were compared between 488 nm and 532 nm cSLO fundus autofluorescence (FAF) images in acute CSC. The mean disease duration and subretinal fluid (SRF) height in the spectral domain optical coherence tomography were compared according to the FAF image characteristics.
결과 : The study included 63 eyes of 61 patients. Before CSC resolution, 48 (76.2%) images of acute CSC were hypo-AF to no change, 3 (4.8%) were hyper-AF, and 12 (19.0%) were mixed-AF in 488 nm FAF images whereas 9 (14.3%) images were hypo-AF to no change, 44 (69.8%) were hyper-AF, and 10 (15.9%) were mixed-AF in 532 nm FAF images (p<0.0001). Patients with lesions that were hyper-AF in 532 nm AF and hypo-AF in 488 nm AF had a shorter disease duration and greater SRF height than those who were hyper-AF in both 532 nm and 488 nm images.
결론 : The two types of FAF image showed similar lesion characteristics in CSC. However, 532 nm AF is more sensitive than 488 nm AF for detecting autofluorescent material in SRF or RPE.
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