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목적 : To comprehend the mechanism of focal chorioretinal damage by analysis of the pressure distribution, flow velocity, and dynamic pressure induced by infused air during fluid-air exchange.
방법 : A precise framework of model eye and fluid circuit was designed to simulate the fluid-air exchange. The pressure distribution, flow velocity, and dynamic pressure induced by infused air in air-filled eye were analyzed by solving the continuity equation and momentum equation. Size of port and infusion pressure were altered for each simulated iteration. Simulation with balanced salt solution (BSS) infusion in air-filled eye was also conducted additionally, for better understanding about the mechanism of chorioretinal damage.
결과 : Infused air was projected straightly toward the point on the part of retina contralateral to the infusion port (vulnerable point). The highest pressure was measured on the vulnerable point while low pressure was recorded on the optic disc head. Higher flow velocity, dynamic pressure and pressure gradient were measured in simulation with greater infusion pressure and larger size port. Pressures on vulnerable point were 2.8 and 5.1 mmHg higher than the pressures on the optic disc with infusion pressure of 30 and 50 mmHg in 20-gauge port throughout the simulation, respectively.
결론 : Our simulation can explain the mechanism of focal chorioretinal damage with numerical representation. Infused air induced prolonged focal pressure increase on vulnerable point may be responsible for the visual field defect after fluid-air exchange.
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