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목적 : Pregnancy is a known predisposing factor for central serous chorioretinopathy (CSC). Choroidal thickness (CT) increases in patients with CSC. This study was designed to evaluate changes in CT during pregnancy
방법 : This was an observational study. Fourteen healthy pregnant women and seven patients with pre-eclampsia were included. Twenty-one normal subjects were also recruited. CT was measured using enhanced-depth imaging optical coherence tomography (EDI-OCT).
결과 : The mean CT values of normal subjects, healthy pregnant women, and patients with pre-eclampsia were 264.95 ± 21.03, 274.23 ± 29.30, and 389.79 ± 25.13 µm, respectively (normal subjects vs. healthy gravidas: P > 0.05; normal subjects vs. pre-eclampsia: P < 0.001; healthy gravidas vs. pre-eclampsia: P < 0.001). CT decreased from 381.05 ± 22.96 µm to 335.17 ± 9.97µm 1 week after delivery in patients with pre-eclampsia.
결론 : Pregnancy itself did not increase CT, whereas pre-eclampsia did appear to result in increased CT. This suggests that additional unknown factors induce hyperpermeability in pregnant women.
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