|
목적 : To investigate postoperative macular ganglion cell-inner plexiform layer (GCIPL) thickness, to determine the factors related to GCIPL thickness, and to evaluate the association of GCIPL thickness with postoperative visual outcomes in patients with idiopathic epiretinal membrane (ERM).
방법 : Sixty-two patients with unilateral idiopathic ERM who were followed up for at least 6 months after surgery were included. Ophthalmologic evaluations included best-corrected visual acuity (BCVA) assessment, spectral-domain optical coherence tomography (SD-OCT), and macular visual field (VF) mean sensitivity (MS) as measured by Humphrey visual field test. Macular GCIPL thickness in eyes with ERM was compared to that of the normal contralateral eyes 6 months after surgery. The correlation between the interocular difference in GCIPL thickness and postoperative visual outcome was evaluated.
결과 : Macular GCIPL thickness was significantly lower in eyes with ERM 6 months after surgery (71.77 ± 10.21 µm) than in the unaffected contralateral eyes (81.69 ± 5.33 µm) (P < 0.001). Preoperative central foveal thickness was the only factor significantly correlated with interocular differences in macular GCIPL thickness (r = 0.3677, P = 0.0033). Among patients with intact photoreceptor layers, a greater decrease in GCIPL thickness was correlated with a worse postoperative BCVA (r = 0.5209, P < 0.0001) and a greater decrease in macular VF MS (dB) (r = -0.2845, P = 0.0390).
결론 : Macular GCIPL thickness decreased after vitrectomy to remove an idiopathic ERM. The decrease in GCIPL thickness was significantly correlated to postoperative visual outcomes in patients with intact photoreceptor layers.
|