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목적 : To identify risk factors for normal-tension glaucoma in patients with myopia.
방법 : Normal-tension glaucoma patients with myopia (range, -1 to -8 D) who had undergone at least 6 visual field tests during follow-up were included. Progression was determined using Glaucoma Progression Analysis, defined as significant deterioration at the same ≥3 points on two or three consecutive tests. Risk factors were analyzed using Cox proportional hazards model and further tested for independence in a multivariate model.
결과 : A total of 41 subjects were analyzed, and 14 subjects showed progression. In the univariate analysis, there were no significant risk factors in age, gender, axial length, central corneal thickness, mean IOP, disc size, vertical cup/disc ratio, baseline visual field mean deviation, and average RNFL thickness. For the 12 clock-hour map on OCT, however, the abnormal color codes of RNFL on 10-, 11-, and 7-o’clock sectors were associated with progression (p<0.1)In the multivariate model, the abnormal RNFL color code of 7-o’clock sector was significant risk factor (hazard ratio 5.02, p<0.05).
결론 : The abnormal color code of RNFL on 7-o’clock sector may represent significant risk factor in myopic patients having normal-tension glaucoma.
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