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목적 : To investigate the relationship between focal lamina cribrosa (LC) defects and myopia using swept-source optical coherence tomography (SS-OCT).
방법 : Two hundred forty-eight eyes of 124 myopic subjects were recruited. All subjects underwent the imaging with the SS-OCT system. According to the spherical equivalent (SE), they were categorized into myopic (<−0.5 diopters) and non-myopic (≥-0.5 diopters) groups. The myopic group was classified into moderately myopic (-6.0 to -0.5 diopters) and highly myopic (<-6.0 diopters) groups. According to the axial length (AXL), they were classified into average (<24.5 mm) and long (≥24.5 mm) groups.
결과 : Out of the 248 eyes, 66 had focal LC defects. Focal LC defects were more prevalent in eyes of the myopic (P = 0.033) and long (P = 0.008) AXL groups. Although no statistically significant difference was observed, focal LC defects occurred more frequently in the highly myopic (38.5%) group than in the moderately myopic and non-myopic (31.3%, 21.6%, respectively; P = 0.100) groups.
결론 : The SS-OCT imaging demonstrates the 3D-structure of LC and allows visualization of focal LC defects. Based on the findings of this study, focal LC defects are significantly associated with myopia.
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