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목적 : To determine the influence of topical anesthetic drops, age and central corneal thickness (CCT) in the determination of intraocular pressure (IOP) by non contact tonometry (NCT).
방법 : 96 eyes from 48 patients were examined for CCT and IOP by NCT before and after the
instillation of topical anesthetic drops. CCT was measured (by non contact pachymeter) prior to IOP determination and IOP was determined prior to, one and five minutes after the instillation of one drop of topical anesthesia (0.5% proparacaine HCl). Each of these determinations was repeated three consecutive times and the average value was used for calculation. The results were compared and the influence of CCT and age was analyzed using descriptive statistics and Student's t-test for paired data.
결과 : Average basal IOP was 16.0mmHg (SD 4.0, range 8.5 to 26.0). IOP 1 minute after topical anesthesia instillation as 15.1mmHg (SD 3.8, range 7.7 to 26.6), and 14.8mmHg (SD 3.9, range 7.6 to 26.2) 5 minutes after the instillation. The differences were statistically significant for the 0 to 1 minute lapse (p=0.0007) and for the 0 to 5 minute lapse (p=0.0003), but not for the 1 to 5 minute lapse (p=0.27). Simple linear regression analysis demonstrated absence of significant variation between age and IOP changes and between CCT and IOP changes.
결론 : Our study confirms that the instillation of topical anesthetics causes a reduction in IOP, which is progressive during the first 5 minutes after instillation. This IOP reduction does not seem to be associated with basal CCT or age.
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