| 발표일자: |
2014년 4월 12일(토) ~ 4월 13일(일) |
| 발표번호: |
P(e-poster)-014 |
| 발표장소: |
킨텍스 제2전시장 7B홀 |
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| Performance of a novel implantable sensor for continuous monitoring of intraocular pressure |
| 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
2Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea
4Korea Institute of Science and Technology, Seoul, Korea
5Department of Electronic Engineering, Sogang University, Seoul, Korea |
| Mi Jeung Kim(1, 2), Ki Ho Park(1, 2), Jin Wook Jeoung(1, 2), Seok Hwan Kim(1, 3), Yong Woo Kim(1, 2), Cheol In Jang(4, 5), Soo Hyun Lee(4), Jae Hun Kim(4), Seok Lee(4), Ji Yoon Kang(4) |
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목적 : To evaluate the preliminary performance and biocompatibility of a novel implantable sensor for continuous monitoring of intraocular pressure (IOP).
방법 : The IOP sensor is composed of a top layer integrated with an inductor and capacitor circuit and a bottom layer integrated with ferrite. IOP change induces mechanical deflection of the bottom layer, which changes the distance between the bottom-layer ferrite and top-layer inductor, resulting in increase of inductance. Thereby, the resonant frequency (RF) decreases, which is detected by an external reader. For a prototype sensor, in-vitro and in-vivo experiments on the rabbit eye were conducted. To validate the biocompatibility, smaller-sized sensors implanted into rabbit eyes were examined.
결과 : In-vitro measurement showed a significant shift of RF, from 10.42 to 9.75 MHz (total shift: 0.67MHz), as pressure was increased from 0 to 25 mmHg. It also showed that over the course of 10 minutes, the RF decreased from 12.80 to 12.67 MHz (total shift: 0.13MHz) as the BSS was infused at the rate of 6µl/min. The microscopic in-vivo evaluations and histological exam showed no evidence of significant inflammation or deformity of the ocular-tissue structures.
결론 : The prototype implantable IOP sensor demonstrated the feasibility of wireless pressure sensing and favorable biocompatibility.
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