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목적 : To evaluate the change in choroidal thickness (CT) between active and quiescent phases of Behcet’s posterior uveitis and compare this to the normal population using enhanced depth imaging optical coherence tomography (EDI-OCT).
방법 : Thirty eyes from 30 patients with Behcet’s posterior uveitis (mean age, 47.03 ± 11.01 years; mean spherical equivalent, -0.952 ± 1.097 diopters) were enrolled in the study. Their subfoveal CT was measured using EDI-OCT in the active phase and quiescent phases of Behcet’s uveitis, and compared with the age, sex, and spherical equivalent-matched normal population. Changes in retinal vascular leakage on fluorescein angiography (FA) were quantified and correlated with the changes in CT.
결과 : Mean subfoveal CT in the acute phase of Behcet uveitis was significantly greater than that in the quiescent phase (398.77 ± 155.59 μm vs 356.72 ± 141.09 μm; p=0.004). CT in the quiescent phase was also significantly greater than that of the normal population (259.96 ± 65.16 μm; p<0.0001). There was a statistically significant association between the change in subfoveal CT and the change in vascular leakage revealed by FA. (ρ = 0.381, p=0.046). Subfoveal CT in the uninvolved fellow eyes of patients with unilateral Behcet’s uveitis was also greater than the normal population. (p=0.001)
결론 : This study found choroidal thickening during the active phase of Behcet’s posterior uveitis. CT during the quiescent phase was also significantly greater than in normal eyes. The degree of reduction in choroidal thickening was significantly correlated with improvement in retinal vascular leakage as revealed by FA.
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