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목적 : To identify the differences of posterior pole profiles between early normal tension glaucoma (NTG) patients with an initial central visual field (VF) loss and those with an peripheral VF loss
방법 : NTG patients with an parafoveal scotoma (PFS ; within a central 10° of fixation) and peripheral nasal step (PNS; VF defect in the nasal meridian outside 10° of fixation) in either hemifield, and normal controls were enrolled in the study. Disc tilt (tilt ratio), disc torsion, area of peripapillary atrophy (PPA), and disc-foveal angle (angle between a horizontal line through the disc center and the line connecting the fovea and the disc center) were analyzed from red-free fundus photographs.
결과 : The mean disc-foveal angles in normal control, PNS and PFS groups were 5.71±3.34°, 6.18 ± 4.53°, and 7.70 ± 3.94°, respectively. In multivariate analysis, eyes with PFS were associated with a greater disc-foveal angle, compared with PNS (P = 0.044). In subgroup analysis, superior PFS group showed greater disc-foveal angle compared to inferior PFS group (P=0.018). In the PNS group, the direction of disc torsion was associated with superior and inferior hemifield defects (P=0.004).
결론 : The posterior pole profiles were different in NTG patients according to their location of damage. Eyes with VF defects at central region have foveas that are more inferiorly located relative to the optic disc than do eyes with peripheral VF defects.
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