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목적 : The mechanism of visual improvement of vitrectomy in diabetic macular edema is not fully understood, despite many studies reporting its effectiveness. Changes in the foveal avascular area on FAG were studied to understand the foveal pathophysiology.
방법 : 55 eyes of 47 patients that underwent vitrectomy and removal of epiretinal membrane for diabetic macular edema were reviewed.
결과 : The early foveal leakage at arterio-venous phase was decreased at 3 and 6 months after vitrectomy (p=0.031). Moreover, the eyes with early foveal leakage before vitrectomy showed the better visual improvement and the more decrease in central macular thickness (p<0.05). On the other hand, the size of foveal avascular zone did not change after vitrectomy and was not related to the visual outcome.
결론 : Vitrectomy effectively reduces leakage around the foveal avascular zone in eyes with diabetic macular edema. The eyes with early foveal leakage may have a more visual benefit from vitrectomy for the management of diabetic macular edema.
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